Aiming at a series of problems such as diet, safety and health caused by the temporary absence of pet guardianship, this paper combines technologies such as the Internet of Things and neural networks to conduct research on an intelligent pet care system. Based on the ZigBee technology of the wireless sensor network and the cloud service platform, this system realizes the real-time monitoring of pet health information and living environment, the intelligent analysis of health data, and the accurate push of care suggestions. This paper makes an in-depth study on the overall architecture of the intelligent cloud-based pet care system and the specific design of software and hardware systems. Through practical deployment and performance testing, the experiment shows that the system operates stably and reliably with an accuracy rate of over 92% in data analysis, and can effectively solve the problem of pet care in the absence of guardianship.