Aiming at the problems of poor independent learning ability of students, single teaching resources, unilateral passive acceptance of knowledge by students, insufficient combination of theoretical and practical classes, insufficient combination of teaching methods and new technologies in traditional teaching of object-oriented programming (C++) course, this teaching innovation proposes a blended teaching plus large model-assisted teaching program, and describes the process of program implementation in detail. The program implements the teaching concept of "student-centered", adopts the teaching mode of “online + offline”, and carries out detailed teaching design and practice of the teaching process from the four dimensions of pre-course, in-course, post-course, and evaluation and feedback, so as to realize all-round enhancement of students' abilities. At the same time, it adopts the large model to assist the teaching implementation, realizing the transformation from "knowledge transmission" to "ability cultivation". The practical results show that the program can realize students' personalized learning, improve students' independent learning ability, increase teacher-student interaction, and enhance the quality of teaching while greatly improving students' social competitiveness.