This study focuses on the application of large AI models and intelligent agents (AI Agents) in the curriculum teaching of institutions of higher education. Given the powerful data processing and deep learning capabilities of large AI models and intelligent agents, this research explores the role of integrating them into programming course teaching in enhancing students' autonomous learning and learning efficiency. This paper proposes an LLM-assisted instructional design framework for teaching, and implements this teaching model through Coze, an intelligent agent tool developed by ByteDance. The results show that this model can significantly enhance students' willingness to learn independently and meet the demands of personalized in-depth learning, providing important references for the teaching reform of vocational colleges.