In the context of the digital age, micro-course, as an online teaching resource, has met the demand for fragmented knowledge in a fast-paced society with its flexibility and efficiency. However, the traditional design and production process of micro-course is complex and time-consuming, making it difficult to adapt to the rapidly developing educational needs. This paper focuses on GenAI technology and proposes a "human-machine collaboration" based micro-course design and production model. Starting from core technologies such as text generation, material creation, application of virtual digital human, and audio-video synthesis, it explores their innovative applications in micro-course production through practical cases. Research shows that GenAI technology can enhance the efficiency of micro-course production and enrich the content of micro-course, but it also faces problems such as technical barriers and limitations in teaching interaction.