Deepening the integration of production and education is a very urgent task to promote the structural reform of the supply side of talents and human resources. The continuous improvement of higher vocational education, deepening the integration of production and education, and school-enterprise cooperation are opportunities for the rapid development of higher vocational education.This article takes the software technology major of Bozhou Vocational and Technical College as an example, expounds the implementation process and the results achieved in the talent training of the integration of production and education and the school-enterprise collaborative education, and provides ideas for the innovative development of other majors and higher vocational colleges.