Based on the characteristics of talent cultivation in higher vocational colleges, in the new stage of "double high" construc-tion, aiming at the current situation of work and study alternation of electronic specialty in higher vocational colleges, this paperfinds out the root causes of the shortage of human resources in enterprises, the unreasonable structure of double quality teachers inschools, the weak practical ability of students, and the imperfect practical education mechanism in schools. It establishes effectiveguarantee system, practice teacher guidance mechanism, electronic innovation second classroom, electronic simulation workshop,apprenticeship mode and work study alternation information platform. The new teaching mode of work and study alternation pro-vides supporting system design, scientific evaluation system, practical training ideas and efficient management mechanism for thecultivation of electronic skilled talents in higher vocational colleges.