In view of the increasing demand for talents in various regions, the demand prediction of talents has become a difficult problem in the current society. In view of this problem, this paper studies on the talent demand forecasting system based on Matlab.First of all, the basic elements of talent are analyzed. Secondly, the framework of talent demand forecasting system is analyzed,and the algorithm flow of BP neural network is described. Finally, the implementation of the system is introduced. This paper has certain positive significance to the regional talent introduction department and software designers.