At present, with the vigorous development of information technology and high-tech in China, the teaching of computer network is becoming more and more important, which becomes the focus of relevant educators. How to train students to be highquality talent has also become an important research topic. The reform and innovation of the teaching activities based on the CDIO can promote the students' enthusiasm and initiative. This paper researches on the teaching design of computer network course based on CDIO, hoping to provide some reference.