With the gradual deepening of educational information, the hybrid teaching mode combining online teaching and classroom teaching has become a common concern. Taking the course of computer application foundation as an example, this paper explores on the hybrid teaching mode combining MOOC-based online learning and traditional classroom teaching. Firstly, it analyzes the connotation and characteristics of MOOC teaching mode, and then points out the advantages and disadvantages of MOOC online teaching mode. Finally, it researches on the realization of hybrid teaching mode based on MOOC for computer application foundation.