With the highlighting of employment puzzles for college students, Internet entrepreneurship based on e-business platform has become the new approach to solve the college students’employment puzzles. However, for the students in minority nationality areas, they have encountered numerous risks for the influence of multi- factors such as region, information and markets, etc. This paper analyzes the present situation and main risks in e-business entrepreneurship for college students in minority nationality areas, and puts forward the relevant risk response countermeasures to provide reference for college students’entrepreneurship.