As a core course of computer system in computer science and technology, the teaching result of Compiling Principle directly affects the students' theoretical knowledge ability and practical ability of computer system. In order to improve the students' knowledge and practical ability of computer system, take the school Taiyuan University of Science and Technology for example, some reform measures such as optimizing the content of classroom teaching, strengthening the process of comprehensive practice, selecting reasonable textbooks and reference books are adopted into the course. Taking the students of grade 2015 as the object of implementation, it is verified that the reform measures can effectively improve the students' theoretical knowledge of computer system and enhance their practical ability of computer system.