The multi-criterion decision analysis method can evaluate the characteristics of a series of alternative schemes based on unrelated and inconsistent criteria, find the characteristics of the optimal decision analysis method, build a spatial multi-criterion decision analysis model based on the hierarchical analysis method, and apply it to the geological disaster susceptibility assessment. Taking landslide disaster in Fujian Province as the research object, the distribution density of disaster points, topography, formation lithology, meteorological conditions and human engineering activities are selected as landslide disaster prone factors, and conducted vulnerability evaluation with MapGIS and SPSS software. Using ROC curve to validate the evaluation results, it is concluded that the ROC curve area of the spatial multi-criterion decision analysis model is 0.852, which shows that the landslide disaster susceptibility evaluation result in Fujian Province is ideal, and it is reasonable to apply the spatial multi-criterion decision analysis model to the landslide disaster susceptibility evaluation.