In industrial automation measurement and control system, real-time database is responsible for the collection, storage, management and monitoring of real-time data. The performance of real-time database determines the accuracy, security and stability of automatic measurement and control, but the application of traditional transactional database in real-time data obviously has the problem of time lag. Therefore, a storage scheme combined with WinCC (Windows Control Center) and SQL Server is designed to improve the database data processing efficiency of automatic measurement and Control system. The scheme has the advantages of high access efficiency and low system pressure, and has certain practical value